ACE Inhibitor and ARB Prices Without Insurance (2025)

ACE Inhibitor and ARB Costs at a Glance

[ACE inhibitors](/drug-classes/ace-inhibitors) and [ARBs](/drug-classes/arbs) are the cornerstone of treatment for [hypertension](/conditions/hypertension), [heart failure](/conditions/heart-failure), and diabetic kidney disease. The good news: virtually all of them are available as inexpensive generics, with many costing $4–$15 per month without insurance.

ACE Inhibitor Price Comparison (30-Day Supply)

ACE Inhibitor	Brand Name	Common Dose	Generic Price
Lisinopril	Prinivil, Zestril	5–40 mg once daily	$4–$10
Enalapril	Vasotec	5–40 mg twice daily	$10–$20
Ramipril	Altace	2.5–20 mg once daily	$15–$30
Benazepril	Lotensin	10–40 mg once daily	$10–$20
Quinapril	Accupril	10–80 mg once daily	$15–$30
Fosinopril	Monopril	10–40 mg once daily	$15–$25
Captopril	Capoten	12.5–150 mg three times daily	$15–$30

ARB Price Comparison (30-Day Supply)

ARB	Brand Name	Common Dose	Generic Price
Losartan	[Cozaar](/drugs/losartan)	25–100 mg once daily	$10–$20
Valsartan	Diovan	80–320 mg once daily	$15–$30
Irbesartan	Avapro	150–300 mg once daily	$15–$30
Olmesartan	Benicar	20–40 mg once daily	$20–$40
Telmisartan	Micardis	40–80 mg once daily	$20–$40
Candesartan	Atacand	8–32 mg once daily	$20–$40
Azilsartan	Edarbi	40–80 mg once daily	$40–$80 (newer generic)

Lisinopril: The Most Affordable Option

Lisinopril is consistently the least expensive ACE inhibitor and one of the cheapest medications of any kind. At $4–$10/month, it is available at Walmart's $4 program and through GoodRx/RxGo coupons at most major pharmacies. It is dosed once daily and has decades of safety and efficacy data.

ACE Inhibitors vs. ARBs: Which Is Cheaper?

ACE inhibitors (particularly [lisinopril](/drugs/lisinopril) and enalapril) are generally cheaper than ARBs. Losartan is the least expensive ARB at $10–$20/month. ARBs are preferred when patients develop ACE inhibitor cough (10–15% of patients) or angioedema.

Sacubitril/Valsartan (Entresto): The Exception

Sacubitril/valsartan (Entresto) is an ARNI — a combination of an ARB (valsartan) and a neprilysin inhibitor (sacubitril). It is preferred over ACE inhibitors for heart failure with reduced ejection fraction but costs $500–$600/month without insurance. A generic version is expected in 2025–2026. Novartis offers a patient assistance program (Entresto Together) for eligible patients.

References

Whelton PK, et al. 2017 ACC/AHA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. J Am Coll Cardiol. 2018;71(19):e127-e248.