Acebutolol Hydrochloride vs. Citalopram
Compare Acebutolol Hydrochloride and Citalopram: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Acebutolol Hydrochloride
Acebutolol Hydrochloride
Beta-Blockers
RxDrug B
Citalopram
Citalopram
SSRIs (Selective Serotonin Reuptake Inhibitors)
RxQuick Comparison
| Category | Acebutolol Hydrochloride | Citalopram |
|---|---|---|
| Drug Class | Beta-Blockers | SSRIs (Selective Serotonin Reuptake Inhibitors) |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $15–$70/month | $4–$25/month |
Acebutolol Hydrochloride Overview
Acebutolol Hydrochloride is a type of medicine called a beta-blocker, primarily used to treat high blood pressure (hypertension) and certain irregular heartbeats (ventricular arrhythmias). It works by relaxing blood vessels and slowing down the heart rate, which helps the heart beat more regularly and reduces the force of blood pumping through your arteries.
Full Acebutolol Hydrochloride guide →Citalopram Overview
Citalopram is a medication called a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder in adults. It works by helping to restore the balance of a natural substance called serotonin in the brain, which can improve mood and feelings of well-being.
Full Citalopram guide →How Each Drug Works
Citalopram
The mechanism of action of citalopram is unclear, but is presumed to be related to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).
Approved Uses (Indications)
Acebutolol Hydrochloride
INDICATIONS AND USAGE Hypertension Acebutolol HCl capsules are indicated for the management of hypertension in adults. It may be used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics. Ventricular Arrhythmias Acebutolol HCl capsules are indicated in the management of ventricular premature beats; it reduces the total number of premature beats, as well as the number of paired and multiform ventricular ectopic beats, and R-on-T beats.
Citalopram
Citalopram is indicated for the treatment of major depressive disorder (MDD) in adults [see Clinical Studies ] . Citalopram is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of major depressive disorder (MDD) in adults .
Side Effects
Acebutolol Hydrochloride
Citalopram
Cost Comparison
Acebutolol Hydrochloride
$15–$70/month
As a generic medication, Acebutolol Hydrochloride is generally affordable. Using discount cards or patient assistance programs can further reduce the cost.
Citalopram
$4–$25/month
As a widely available generic, Citalopram is very affordable. Using discount cards like GoodRx can further reduce the cost to just a few dollars per month.
Drug Interaction: Moderate
The co-administration of acebutolol and citalopram may lead to an increased risk of bradycardia and hypotension. Citalopram is a weak inhibitor of CYP2D6, which is involved in the metabolism of acebutolol, potentially increasing acebutolol plasma concentrations. Both drugs can also independently cause bradycardia.
Mechanism: Acebutolol is metabolized by CYP2D6. Citalopram is a weak inhibitor of CYP2D6, which may reduce the metabolism of acebutolol, leading to increased acebutolol plasma levels and enhanced beta-blocking effects. Additionally, both acebutolol and citalopram can independently cause bradycardia, leading to an additive pharmacodynamic effect.
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.