ACE Inhibitors
Blood pressure medications that block angiotensin-converting enzyme.
Mechanism of Action
ACE Inhibitors work by blocking a specific enzyme in your body called Angiotensin-Converting Enzyme (ACE). This enzyme normally helps create a powerful chemical called angiotensin II, which narrows blood vessels and tells your body to hold onto salt and water. By blocking ACE, these medicines relax your blood vessels, making them wider, and help your body get rid of extra salt and water. This process lowers blood pressure and makes it easier for your heart to pump blood.
Clinical Uses
This class of drugs is primarily used to treat high blood pressure (hypertension) and heart failure, helping to improve heart function and reduce symptoms. They are also commonly prescribed after a heart attack to protect the heart and prevent future problems. For people with diabetes, ACE inhibitors can help protect the kidneys from damage, even if blood pressure is not high.
Side Effects & Safety
Common side effects include a dry, persistent cough, dizziness (especially when standing up), and fatigue. More serious, but rare, side effects can include swelling of the face, lips, tongue, or throat (angioedema), and kidney problems. These medications should not be used during pregnancy due to a risk of harm to the unborn baby.
Conditions Treated
ACE Inhibitors medications are used to treat the following conditions:
ACE Inhibitors Medications (11)
Benazepril hydrochloride
Brand: Benazepril Hydrochloride
Benazepril is a medication in a class called ACE inhibitors, primarily used to treat high blood pressure. It works by relaxing blood vessels, which helps lower blood pressure and reduces the risk of serious heart problems like strokes and heart attacks.
$50–$150/month/month
Captopril
Brand: Captopril
Captopril is a medication belonging to a class of drugs called ACE inhibitors, primarily used to treat high blood pressure (hypertension). It works by helping to relax blood vessels, which allows blood to flow more easily and lowers blood pressure.
$10–$40/month/month
Enalapril maleate
Brand: Enalapril Maleate
Enalapril maleate is a medication called an ACE inhibitor, primarily used to treat high blood pressure and heart failure. It works by relaxing blood vessels, which helps lower blood pressure and makes it easier for your heart to pump blood. This can improve symptoms and overall heart function.
$4-$15/month/month
Fosinopril
Brand: Monopril
Fosinopril (Monopril) is an ACE inhibitor used to treat high blood pressure (hypertension) and heart failure. It works by blocking angiotensin-converting enzyme, relaxing blood vessels and reducing the workload on the heart.
$10–$30/month/month
Lisinopril
Brand: Prinivil, Zestril, Zestoretic (with hydrochlorothiazide) +1 more
Lisinopril (Prinivil, Zestril) is one of the most widely prescribed medications in the United States and the most commonly used ACE inhibitor. It lowers blood pressure by relaxing blood vessels, reduces hospitalizations and death in heart failure, and improves survival after a heart attack. It is also used to slow kidney disease progression in people with diabetes. Generic lisinopril is available for as little as $4–$15 per month, making it one of the most cost-effective cardiovascular medications available.
$4–$15/month/month
Moexipril hydrochloride
Brand: Moexipril Hydrochloride
Moexipril Hydrochloride is a medication used to treat high blood pressure (hypertension). It belongs to a group of drugs called ACE inhibitors, which work by relaxing blood vessels to help lower blood pressure and improve blood flow. This helps reduce the risk of heart problems and strokes.
$200–$500/month/month
Perindopril erbumine
Brand: Perindopril Erbumine
Perindopril Erbumine is an ACE inhibitor medication used to treat high blood pressure (hypertension) and to reduce the risk of heart attack or death in people with stable coronary artery disease. It works by relaxing blood vessels, which helps lower blood pressure and makes it easier for the heart to pump blood.
$50–$150/month/month
Quinapril
Brand: Quinapril
Quinapril is a medication used to treat high blood pressure. It works by relaxing blood vessels, which helps to lower blood pressure and reduce the risk of serious heart problems like strokes and heart attacks.
$200–$500/month/month
Quinapril hydrochloride
Brand: Quinapril
Quinapril (Quinapril Hydrochloride) is a medication used to treat high blood pressure. It belongs to a group of drugs called ACE inhibitors, which work by relaxing blood vessels, allowing blood to flow more easily and lowering the pressure on artery walls. By reducing high blood pressure, Quinapril helps decrease the risk of serious heart problems like strokes and heart attacks.
$150–$400/month/month
Ramipril
Brand: Ramipril
Ramipril is a medication in a class called ACE inhibitors, primarily used to treat high blood pressure. By helping to relax your blood vessels, it lowers blood pressure and can also reduce the risk of heart attack, stroke, and help manage heart failure after a heart attack.
$4–$25/month/month
Trandolapril
Brand: Mavik
Trandolapril is a medication used to treat high blood pressure (hypertension) and to improve outcomes for certain patients after a heart attack. It works by relaxing blood vessels so the heart does not have to work as hard to pump blood.
$100–$300/month/month
Compare ACE Inhibitors Prices
See typical monthly costs, generic availability, and savings options for all 11 ACE Inhibitors medications side-by-side.
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.