Medications for Obesity
ICD-10: E66
Medically Reviewed by Dr. Sarah Chen, PharmD, BCPS
Clinical Pharmacist & Medical Reviewer
Last reviewed: March 19, 2026
Overview
Obesity affects 42% of American adults and is a major risk factor for type 2 diabetes, cardiovascular disease, sleep apnea, and certain cancers. It is now recognized as a chronic disease requiring long-term management.
Treatment Overview
Treatment includes intensive lifestyle intervention, behavioral therapy, pharmacotherapy, and bariatric surgery for severe cases. GLP-1 receptor agonists represent a major advance in pharmacological treatment.
7
Total Medications
0
First-Line Options
1
Off-Label Uses
Frequently Asked Questions
What BMI is considered obese?
A BMI of 30 or higher is classified as obese. Class I obesity: BMI 30–34.9. Class II: BMI 35–39.9. Class III (severe): BMI ≥ 40.
Find the lowest price for any medication
Real-time prices at 67,000+ pharmacies · Free · No sign-up
Protect your muscle mass on GLP-1 medications
GLP-1 medications can cause up to 39% muscle loss alongside fat. Zova's AI-powered protocol — backed by Lancet Diabetes & Endocrinology research — reduces that to just 8.7% through leucine tracking and injection-day adaptive nutrition.
No credit card. No commitment.
Get the RxGo app — free prescription discounts on the go
Works at 67,000+ pharmacies · No membership needed
Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.