Condition Guide

Medications for Hypertension (High Blood Pressure)

ICD-10: I10

Medically Reviewed by Dr. Sarah Chen, PharmD, BCPS

Clinical Pharmacist & Medical Reviewer

Last reviewed: March 19, 2026

Overview

Hypertension affects nearly half of American adults and is a major risk factor for heart disease, stroke, and kidney disease. It is often called the 'silent killer' because it typically has no symptoms.

Treatment Overview

Treatment includes lifestyle changes (DASH diet, exercise, sodium reduction, weight loss) and medications. First-line drug classes include ACE inhibitors, ARBs, thiazide diuretics, and calcium channel blockers.

Total Medications

First-Line Options

Off-Label Uses

atorvastatin

(atorvastatin calcium)Off-Label

Atorvastatin (Lipitor) is a medication that belongs to a class of drugs called statins. It is primarily used to lower high cholesterol levels in the blood and reduce the risk of serious heart problems like heart attack and stroke. It works by helping your body produce less cholesterol.

$4–$25/month

Frequently Asked Questions

What blood pressure reading is considered high?

A blood pressure of 130/80 mmHg or higher is classified as hypertension by current guidelines. Normal blood pressure is below 120/80 mmHg.

Medical Disclaimer

The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.