Aspirin vs. Ibuprofen
Compare Aspirin and Ibuprofen: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Aspirin
Aspirin Regular Strength
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
RxDrug B
Ibuprofen
good neighbor pharmacy ibuprofen
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
RxQuick Comparison
| Category | Aspirin | Ibuprofen |
|---|---|---|
| Drug Class | NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) | NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $5–$20/month | $4-$15/month |
Aspirin Overview
ASPIRIN (brand name: Aspirin Regular Strength) is a NSAIDs. Uses temporarily relieves: headache muscle pain toothache menstrual pain pain and fever of colds minor pain of arthritis
Full Aspirin guide →Ibuprofen Overview
IBUPROFEN (brand name: good neighbor pharmacy ibuprofen) is a NSAIDs. Uses • temporarily relieves minor aches and pains due to: • headache • muscular aches • minor pain of arthritis • toothache • backache • the common cold • menstrual cramps • temporarily reduces fever
Full Ibuprofen guide →Approved Uses (Indications)
Aspirin
Uses temporarily relieves: headache muscle pain toothache menstrual pain pain and fever of colds minor pain of arthritis
Ibuprofen
Uses
- temporarily relieves minor aches and pains due to:
- headache
- muscular aches
- minor pain of arthritis
- toothache
- backache
- the common cold
- menstrual cramps
- temporarily reduces fever
Cost Comparison
Aspirin
$5–$20/month
Aspirin is available over-the-counter at a very low cost, often less than $5 for a large supply. Discount cards can sometimes offer minor savings on the prescription version, but it's generally more cost-effective to buy OTC.
Ibuprofen
$4-$15/month
Ibuprofen is widely available as an inexpensive generic, even without insurance. Discount cards can further reduce the cost at many pharmacies.
Drug Interaction: Moderate
Ibuprofen can interfere with the antiplatelet effect of low-dose aspirin, which is used for cardiovascular prophylaxis. This interaction may reduce aspirin's ability to prevent blood clots, potentially increasing the risk of cardiovascular events.
Mechanism: Ibuprofen, by reversibly binding to the cyclooxygenase-1 (COX-1) enzyme, can block aspirin's irreversible binding site. If ibuprofen is taken before aspirin, it prevents aspirin from acetylating COX-1 in platelets, thereby diminishing aspirin's antiplatelet effect.
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Medical Disclaimer
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