Combining Atenolol and Diltiazem Hydrochloride is a major interaction and should generally be avoided without close medical supervision.
Concurrent use of atenolol and diltiazem increases the risk of bradycardia, heart block, and hypotension.
Mechanism: Both drugs slow conduction through the AV node and reduce heart rate through complementary mechanisms.
Atenolol vs. Diltiazem Hydrochloride
Compare Atenolol and Diltiazem Hydrochloride: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Atenolol
Atenolol
Beta-Blockers
RxDrug B
Diltiazem Hydrochloride
Diltiazem Hydrochloride
Calcium Channel Blockers
RxQuick Comparison
| Category | Atenolol | Diltiazem Hydrochloride |
|---|---|---|
| Drug Class | Beta-Blockers | Calcium Channel Blockers |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $4–$25/month | $10–$50/month |
Atenolol Overview
Atenolol is a medication used to treat high blood pressure. It works by helping to relax blood vessels and slow down your heart rate, which lowers your blood pressure and reduces the risk of serious heart problems like strokes and heart attacks.
Full Atenolol guide →Diltiazem Hydrochloride Overview
Diltiazem Hydrochloride is a calcium channel blocker medication used to treat certain heart conditions. It works by relaxing blood vessels, which helps to improve blood flow to the heart. This medication is primarily prescribed to manage chest pain (angina) caused by heart disease or spasms in the heart's arteries.
Full Diltiazem Hydrochloride guide →How Each Drug Works
Diltiazem Hydrochloride
Mechanisms of Action Although precise mechanisms of its antianginal actions are still being delineated, diltiazem hydrochloride is believed to act in the following ways: Angina Due to Coronary Artery Spasm: Diltiazem hydrochloride has been shown to be a potent dilator of coronary arteries both epicardial and subendocardial. Spontaneous and ergonovine-induced coronary artery spasms are inhibited by diltiazem hydrochloride. Exertional Angina: Diltiazem hydrochloride has been shown to produce incre…
Approved Uses (Indications)
Atenolol
INDICATIONS AND USAGE Hypertension Atenolol is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including atenolol. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise…
Diltiazem Hydrochloride
INDICATIONS AND USAGE Diltiazem hydrochloride tablets are indicated for the management of chronic stable angina and angina due to coronary artery spasm.
Side Effects
Atenolol
Diltiazem Hydrochloride
Cost Comparison
Atenolol
$4–$25/month
Since Atenolol is available as a generic, significant savings can be achieved by opting for the generic version. Using discount cards like GoodRx can further reduce the out-of-pocket cost.
Diltiazem Hydrochloride
$10–$50/month
Diltiazem Hydrochloride is a widely available generic, making it very affordable. Using a discount card like GoodRx can often reduce the cost to under $15 per month without insurance.
Compare prices for Atenolol and Diltiazem Hydrochloride
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.