Carvedilol vs. Fluoxetine HCl
Compare Carvedilol and Fluoxetine HCl: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Carvedilol
Carvedilol
Beta-Blockers
RxDrug B
Fluoxetine HCl
Fluoxetine HCL
SSRIs (Selective Serotonin Reuptake Inhibitors)
RxQuick Comparison
| Category | Carvedilol | Fluoxetine HCl |
|---|---|---|
| Drug Class | Beta-Blockers | SSRIs (Selective Serotonin Reuptake Inhibitors) |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $4-$25/month | $4-$25/month |
Carvedilol Overview
Carvedilol is a medication known as an alpha and beta blocker. It is prescribed to treat conditions such as high blood pressure, chronic heart failure, and to improve outcomes after a heart attack. Carvedilol works by relaxing blood vessels and slowing the heart rate, which helps the heart pump blood more easily and efficiently.
Full Carvedilol guide →Fluoxetine HCl Overview
FLUOXETINE HCL (brand name: Fluoxetine HCL) is a SSRIs. Fluoxetine is indicated for the treatment of: Acute and maintenance treatment of Major Depressive Disorder [see CLINICAL STUDIES (14.1)] . Acute and maintenance treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder (OCD) [see CLINICAL STUDIES (14.2)] . Acute and…
Full Fluoxetine HCl guide →How Each Drug Works
Carvedilol
Carvedilol is a racemic mixture in which nonselective β-adrenoreceptor blocking activity is present in the S(-) enantiomer and α 1 -adrenergic blocking activity is present in both R(+) and S(-) enantiomers at equal potency. Carvedilol has no intrinsic sympathomimetic activity.
Approved Uses (Indications)
Carvedilol
Carvedilol tablets are an alpha-/beta-adrenergic blocking agent indicated for the treatment of: mild to severe chronic heart failure left ventricular dysfunction following myocardial infarction in clinically stable patients hypertension 1.1 Heart Failure Carvedilol tablets are indicated for the treatment of mild-to-severe chronic heart failure of ischemic or cardiomyopathic origin, usually in addition to diuretics, ACE inhibitors, and digitalis, to increase survival and, also, to reduce the risk of hospitalization [see Drug Interactions , …
Fluoxetine HCl
Fluoxetine is indicated for the treatment of: Acute and maintenance treatment of Major Depressive Disorder [see CLINICAL STUDIES ] . Acute and maintenance treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder (OCD) [see CLINICAL STUDIES ] . Acute and maintenance treatment of binge-eating and vomiting behaviors in patients with moderate to severe Bulimia Nervosa [see CLINICAL STUDIES ] . Acute treatment of Panic Disorder, with or without agoraphobia [see CLINICAL STUDIES ] . Fluoxetine and Olanzapine in Combination is indicated for the tr…
Side Effects
Carvedilol
Fluoxetine HCl
Cost Comparison
Carvedilol
$4-$25/month
As a widely available generic, Carvedilol is typically inexpensive. Using discount cards or pharmacy loyalty programs can further reduce the cost.
Fluoxetine HCl
$4-$25/month
As a widely available generic, Fluoxetine HCl is very affordable. Patients can often find significant savings using discount cards or by checking prices at different pharmacies.
Drug Interaction: Moderate
Fluoxetine inhibits CYP2D6, increasing carvedilol plasma levels and potentially causing excessive beta-blockade.
Mechanism: Carvedilol is primarily metabolized by CYP2D6. Fluoxetine's CYP2D6 inhibition increases carvedilol AUC by up to 77%.
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Medical Disclaimer
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