Chlordiazepoxide Hydrochloride and Fentanyl must not be used together. This combination is classified as CONTRAINDICATED.
Concomitant use can lead to severe adverse effects including profound sedation, respiratory depression, coma, and death. Patients may exhibit decreased level of consciousness, hypoventilation, hypoxia, and hypotension.
Mechanism: Fentanyl, an opioid agonist, and chlordiazepoxide, a benzodiazepine, both act as central nervous system (CNS) depressants. Their co-administration results in an additive and synergistic depressant effect on the CNS, particularly on brainstem respiratory centers, leading to profound respiratory depression.
Chlordiazepoxide Hydrochloride vs. Fentanyl
Compare Chlordiazepoxide Hydrochloride and Fentanyl: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Chlordiazepoxide Hydrochloride
Chlordiazepoxide Hydrochloride
Benzodiazepines
RxDrug B
Fentanyl
Fentanyl
Opioid Analgesics
RxQuick Comparison
| Category | Chlordiazepoxide Hydrochloride | Fentanyl |
|---|---|---|
| Drug Class | Benzodiazepines | Opioid Analgesics |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $10-$40/month | $150–$600/month |
Chlordiazepoxide Hydrochloride Overview
Chlordiazepoxide Hydrochloride is a benzodiazepine medication used to treat anxiety disorders and provide short-term relief for symptoms of anxiety. It can also help manage withdrawal symptoms from acute alcoholism and reduce anxiety before surgery. This medication works by calming the brain and nerves.
Full Chlordiazepoxide Hydrochloride guide →Fentanyl Overview
FENTANYL (brand name: FENTANYL) is a Opioid Analgesics. 1 INDICATIONS AND USAGE Fentanyl transdermal system is indicated for the management of severe and persistent pain in opioid-tolerant patients, that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids. Patients considered…
Full Fentanyl guide →How Each Drug Works
Fentanyl
Fentanyl is an opioid agonist. Fentanyl interacts predominately with the opioid mu-receptor. These mu-binding sites are distributed in the human brain, spinal cord, and other tissues.
Approved Uses (Indications)
Chlordiazepoxide Hydrochloride
INDICATIONS AND USAGE Chlordiazepoxide HCl capsules are indicated for the management of anxiety disorders or for the short term relief of symptoms of anxiety, withdrawal symptoms of acute alcoholism, and preoperative apprehension and anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. The effectiveness of chlordiazepoxide HCl capsules in long term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individua…
Fentanyl
Fentanyl transdermal system is indicated for the management of severe and persistent pain in opioid-tolerant patients, that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids. Patients considered opioid-tolerant are those who are taking, for one week or longer, at least 60 mg morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg oral oxycodone per day, 8 mg oral hydromorphone per day, 25 mg oral oxymorphone per day, 60 mg oral hydrocodone per day, or an equianalgesic dose of another op…
Side Effects
Chlordiazepoxide Hydrochloride
Fentanyl
Cost Comparison
Chlordiazepoxide Hydrochloride
$10-$40/month
As a generic medication, Chlordiazepoxide Hydrochloride is relatively inexpensive. Using discount cards like GoodRx can often reduce the cost further, sometimes to less than $10 per month.
Fentanyl
$150–$600/month
As a brand-only medication, fentanyl can be expensive. Patients should check for manufacturer coupons or patient assistance programs, and compare prices at different pharmacies using discount cards.
Compare prices for Chlordiazepoxide Hydrochloride and Fentanyl
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.