Citalopram and Escitalopram Oral must not be used together. This combination is classified as CONTRAINDICATED.
Combining escitalopram and citalopram is pharmacologically redundant and doubles the QT-prolongation risk.
Mechanism: Both drugs are the same pharmacological entity (escitalopram is the active S-enantiomer of citalopram). Concurrent use doubles the dose and QTc-prolonging effect.
Citalopram vs. Escitalopram Oral
Compare Citalopram and Escitalopram Oral: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Citalopram
Citalopram
SSRIs (Selective Serotonin Reuptake Inhibitors)
RxDrug B
Escitalopram Oral
Escitalopram Oral Solution
SSRIs (Selective Serotonin Reuptake Inhibitors)
RxQuick Comparison
| Category | Citalopram | Escitalopram Oral |
|---|---|---|
| Drug Class | SSRIs (Selective Serotonin Reuptake Inhibitors) | SSRIs (Selective Serotonin Reuptake Inhibitors) |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $4–$25/month | $200–$500/month |
Citalopram Overview
Citalopram is a medication called a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder in adults. It works by helping to restore the balance of a natural substance called serotonin in the brain, which can improve mood and feelings of well-being.
Full Citalopram guide →Escitalopram Oral Overview
Escitalopram oral is a medication known as an antidepressant (specifically, an SSRI) that helps improve mood. It is primarily used to treat major depressive disorder in adults and children aged 12 and older, as well as generalized anxiety disorder in adults, by helping to restore the balance of certain natural substances in the brain.
Full Escitalopram Oral guide →How Each Drug Works
Citalopram
The mechanism of action of citalopram is unclear, but is presumed to be related to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).
Approved Uses (Indications)
Citalopram
Citalopram is indicated for the treatment of major depressive disorder (MDD) in adults [see Clinical Studies ] . Citalopram is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of major depressive disorder (MDD) in adults .
Escitalopram Oral
Escitalopram is indicated for the treatment of: major depressive disorder (MDD) in adults and pediatric patients 12 years of age and older. generalized anxiety disorder (GAD) in adults. Additional pediatric use information is approved for AbbVie Inc.’s Lexapro (escitalopram) tablets and LEXAPRO (escitalopram) oral solution. However, due to AbbVie Inc.’s marketing exclusivity rights, this drug product is not labeled with that information. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) indicated for the: treatment of major depressive disorder (MDD) in adu…
Side Effects
Citalopram
Escitalopram Oral
Cost Comparison
Citalopram
$4–$25/month
As a widely available generic, Citalopram is very affordable. Using discount cards like GoodRx can further reduce the cost to just a few dollars per month.
Escitalopram Oral
$200–$500/month
Since a generic is not available for the oral solution, look for manufacturer coupons or patient assistance programs to help reduce the cost. Discount cards may also offer some savings.
Compare prices for Citalopram and Escitalopram Oral
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.