Citalopram vs. Labetalol
Compare Citalopram and Labetalol: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Citalopram
Citalopram
SSRIs (Selective Serotonin Reuptake Inhibitors)
RxDrug B
Labetalol
Labetalol Hydrochloride
Beta-Blockers
RxQuick Comparison
| Category | Citalopram | Labetalol |
|---|---|---|
| Drug Class | SSRIs (Selective Serotonin Reuptake Inhibitors) | Beta-Blockers |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $4–$25/month | $10–$40/month |
Citalopram Overview
Citalopram is a medication called a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder in adults. It works by helping to restore the balance of a natural substance called serotonin in the brain, which can improve mood and feelings of well-being.
Full Citalopram guide →Labetalol Overview
Labetalol is a medication used to treat high blood pressure (hypertension). It works by relaxing blood vessels and slowing the heart rate, which helps to lower your blood pressure. This can reduce the risk of complications like heart attack and stroke.
Full Labetalol guide →How Each Drug Works
Citalopram
The mechanism of action of citalopram is unclear, but is presumed to be related to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).
Approved Uses (Indications)
Citalopram
Citalopram is indicated for the treatment of major depressive disorder (MDD) in adults [see Clinical Studies ] . Citalopram is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of major depressive disorder (MDD) in adults .
Labetalol
INDICATIONS AND USAGE Labetalol hydrochloride tablets, USP are indicated in the management of hypertension. Labetalol hydrochloride tablets, USP may be used alone or in combination with other antihypertensive agents, especially thiazide and loop diuretics.
Side Effects
Citalopram
Labetalol
Cost Comparison
Citalopram
$4–$25/month
As a widely available generic, Citalopram is very affordable. Using discount cards like GoodRx can further reduce the cost to just a few dollars per month.
Labetalol
$10–$40/month
Generic labetalol is widely available and typically affordable. Using discount cards or coupons can further reduce the out-of-pocket cost.
Drug Interaction: Minor
Labetalol is primarily metabolized by CYP2D6, while citalopram is a weak inhibitor of CYP2D6. This interaction is generally not considered clinically significant, but theoretically, it could lead to a slight increase in labetalol levels.
Mechanism: Citalopram is a weak inhibitor of CYP2D6, the primary enzyme responsible for labetalol metabolism. This could potentially reduce the clearance of labetalol, leading to increased plasma concentrations.
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.