Citalopram vs. Metoprolol Succinate
Compare Citalopram and Metoprolol Succinate: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Citalopram
Citalopram
SSRIs (Selective Serotonin Reuptake Inhibitors)
RxDrug B
Metoprolol Succinate
Metoprolol Succinate
Beta-Blockers
RxQuick Comparison
| Category | Citalopram | Metoprolol Succinate |
|---|---|---|
| Drug Class | SSRIs (Selective Serotonin Reuptake Inhibitors) | Beta-Blockers |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $4–$25/month | $4-$25/month |
Citalopram Overview
Citalopram is a medication called a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder in adults. It works by helping to restore the balance of a natural substance called serotonin in the brain, which can improve mood and feelings of well-being.
Full Citalopram guide →Metoprolol Succinate Overview
METOPROLOL SUCCINATE (brand name: Metoprolol Succinate) is a Beta-Blockers. 1 INDICATIONS & USAGE Metoprolol succinate extended-release tablets, metoprolol succinate, beta-adrenergic blocker indicated for the treatment of: • Hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and…
Full Metoprolol Succinate guide →How Each Drug Works
Citalopram
The mechanism of action of citalopram is unclear, but is presumed to be related to potentiation of serotonergic activity in the central nervous system (CNS) resulting from its inhibition of CNS neuronal reuptake of serotonin (5-HT).
Approved Uses (Indications)
Citalopram
Citalopram is indicated for the treatment of major depressive disorder (MDD) in adults [see Clinical Studies ] . Citalopram is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of major depressive disorder (MDD) in adults .
Metoprolol Succinate
Metoprolol succinate extended-release tablets, metoprolol succinate, beta-adrenergic blocker indicated for the treatment of:
- Hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.()
- Angina Pectoris. ()
- Heart Failure, to reduce the risk of cardiovascular mortality and heart failure hospitalizations in patients with heart failure() 1.1 Hypertension Metoprolol succinate extended-release tablets is indicated for the treatment of hypertension, to lower blo…
Side Effects
Citalopram
Metoprolol Succinate
Cost Comparison
Citalopram
$4–$25/month
As a widely available generic, Citalopram is very affordable. Using discount cards like GoodRx can further reduce the cost to just a few dollars per month.
Metoprolol Succinate
$4-$25/month
Metoprolol Succinate is available as a low-cost generic. Patients can often find significant savings by using discount cards or patient assistance programs.
Drug Interaction: Moderate
Citalopram is a weak inhibitor of CYP2D6, which is the primary enzyme metabolizing metoprolol. This interaction can lead to increased plasma concentrations of metoprolol, potentially enhancing its beta-blocking effects and increasing the risk of bradycardia and hypotension.
Mechanism: Citalopram weakly inhibits cytochrome P450 2D6 (CYP2D6). Metoprolol is extensively metabolized by CYP2D6, so citalopram can decrease metoprolol's metabolic clearance, leading to elevated systemic exposure.
Compare prices for Citalopram and Metoprolol Succinate
Check real-time pharmacy prices before you fill — free, no account needed.
Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.