Combining Cyclobenzaprine Hydrochloride and Oxymorphone Hydrochloride is a major interaction and should generally be avoided without close medical supervision.
Patients may experience profound sedation, somnolence, dizziness, and impaired psychomotor function. The most serious clinical effect is an increased risk of respiratory depression, which can be life-threatening, along with hypotension and coma.
Mechanism: Both oxymorphone, an opioid agonist, and cyclobenzaprine, a centrally acting muscle relaxant with anticholinergic properties, cause central nervous system (CNS) depression. Their co-administration leads to an additive depressant effect on the brain and spinal cord, exacerbating sedation and respiratory depression.
Cyclobenzaprine Hydrochloride vs. Oxymorphone Hydrochloride
Compare Cyclobenzaprine Hydrochloride and Oxymorphone Hydrochloride: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Cyclobenzaprine Hydrochloride
Cyclobenzaprine Hydrochloride
Skeletal Muscle Relaxants
RxDrug B
Oxymorphone Hydrochloride
Oxymorphone Hydrochloride
Opioid Analgesics
RxQuick Comparison
| Category | Cyclobenzaprine Hydrochloride | Oxymorphone Hydrochloride |
|---|---|---|
| Drug Class | Skeletal Muscle Relaxants | Opioid Analgesics |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $10–$30/month | $200–$800/month |
Cyclobenzaprine Hydrochloride Overview
Cyclobenzaprine Hydrochloride is a muscle relaxant medication used to relieve muscle spasms caused by acute, painful muscle and bone conditions. It works by helping to relax the muscles, which can reduce pain, tenderness, and improve movement when used with rest and physical therapy. This medication is typically used for short periods to help you recover from these types of injuries.
Full Cyclobenzaprine Hydrochloride guide →Oxymorphone Hydrochloride Overview
OXYMORPHONE HYDROCHLORIDE (brand name: Oxymorphone Hydrochloride) is a Opioid Analgesics. 1 INDICATIONS AND USAGE Oxymorphone hydrochloride tablets are indicated for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction, abuse, misuse, overdose, and death, which…
Full Oxymorphone Hydrochloride guide →How Each Drug Works
Oxymorphone Hydrochloride
Oxymorphone is a full opioid agonist and is relatively selective for the mu-opioid receptor, although it can bind to other opioid receptors at higher doses. The principal therapeutic action of oxymorphone is analgesia. Like all full opioid agonists, there is no ceiling effect for analgesia with oxymorphone. Clinically, dosage is titrated to provide adequate analgesia and may be limited by adverse reactions, including respiratory and CNS depression. The precise mechanism …
Approved Uses (Indications)
Cyclobenzaprine Hydrochloride
INDICATIONS AND USAGE Cyclobenzaprine hydrochloride tablets are indicated as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions. Improvement is manifested by relief of muscle spasm and its associated signs and symptoms, namely, pain, tenderness, limitation of motion, and restriction in activities of daily living. Cyclobenzaprine hydrochloride tablets should be used only for short periods (up to two or three weeks) because adequate evidence of effectiveness for more prolonged use is not available and because muscle spasm …
Oxymorphone Hydrochloride
Oxymorphone hydrochloride tablets are indicated for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Limitations of Use Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration, and persist over the course of therapy [see Warnings and Precautions ] , reserve opioid analgesics, including oxymorphone hydrochloride for use in patients for whom alternative treatment options are ineffective, not tolerated, or would be otherwise inadequate…
Side Effects
Cyclobenzaprine Hydrochloride
Oxymorphone Hydrochloride
Cost Comparison
Cyclobenzaprine Hydrochloride
$10–$30/month
As a widely available generic, Cyclobenzaprine Hydrochloride is very affordable, especially with discount cards like GoodRx. Always compare prices at different pharmacies and consider using a coupon.
Oxymorphone Hydrochloride
$200–$800/month
Since a generic is not available, patients may find discounts using manufacturer coupons or patient assistance programs. Comparing prices at different pharmacies with discount cards can also help reduce costs.
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.