Combining Dipyridamole and Ketorolac Tromethamine is a major interaction and should generally be avoided without close medical supervision.
Combining ketorolac (an NSAID) with dipyridamole (an antiplatelet) significantly increases your risk of bleeding, particularly in the stomach or intestines. This combination should generally be avoided.
Mechanism: Ketorolac inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis and impairing platelet aggregation. Dipyridamole also inhibits platelet aggregation by increasing cyclic AMP levels. The concurrent use of two agents that inhibit platelet function leads to an additive antiplatelet effect.
Dipyridamole vs. Ketorolac Tromethamine
Compare Dipyridamole and Ketorolac Tromethamine: mechanism of action, indications, side effects, cost, and which may be right for you.
Drug A
Dipyridamole
Dipyridamole
Antiplatelet Agents
RxDrug B
Ketorolac Tromethamine
Ketorolac Tromethamine
NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
RxQuick Comparison
| Category | Dipyridamole | Ketorolac Tromethamine |
|---|---|---|
| Drug Class | Antiplatelet Agents | NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) |
| Rx Status | Rx | Rx |
| Generic Available | No | No |
| Typical Cost | $150–$400/month | $10–$50/month |
Dipyridamole Overview
Dipyridamole is a medication that helps prevent blood clots. It works by making platelets, tiny blood cells involved in clotting, less sticky. This medicine is primarily used alongside other blood thinners to prevent dangerous blood clots after heart valve replacement surgery.
Full Dipyridamole guide →Ketorolac Tromethamine Overview
KETOROLAC TROMETHAMINE (brand name: Ketorolac Tromethamine) is a NSAIDs. INDICATIONS AND USAGE Carefully consider the potential benefits and risks of Ketorolac Tromethamine Tablets USP and other treatment options before deciding to use Ketorolac Tromethamine Tablets USP. Use the lowest effective dose for the shortest duration consistent with individual patient treatment…
Full Ketorolac Tromethamine guide →How Each Drug Works
Dipyridamole
Mechanism of Action Dipyridamole inhibits the uptake of adenosine into platelets, endothelial cells and erythrocytes in vitro and in vivo ; the inhibition occurs in a dose-dependent manner at therapeutic concentrations (0.5 mcg/mL to 1.9 mcg/mL). This inhibition results in an increase in local concentrations of adenosine which acts on the platelet A 2 -receptor thereby stimulating platelet adenylate cyclase and increasing platelet cyclic-3',5'-adenosine monophosphate (cAMP) levels. Via this mech…
Approved Uses (Indications)
Dipyridamole
INDICATIONS AND USAGE Dipyridamole tablets are indicated as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement.
Ketorolac Tromethamine
INDICATIONS AND USAGE Carefully consider the potential benefits and risks of Ketorolac Tromethamine Tablets USP and other treatment options before deciding to use Ketorolac Tromethamine Tablets USP. Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. Acute Pain in Adult Patients Ketorolac Tromethamine Tablets USP are indicated for the short-term (≤ 5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting. Therapy should always be initiated with IV or IM dosing of ke…
Side Effects
Dipyridamole
Ketorolac Tromethamine
Cost Comparison
Dipyridamole
$150–$400/month
Since Dipyridamole is only available as a brand-name drug, look for manufacturer coupons or patient assistance programs to help reduce the cost. Discount cards like GoodRx may also offer savings.
Ketorolac Tromethamine
$10–$50/month
As a widely available generic, Ketorolac Tromethamine is typically inexpensive. Using discount cards like GoodRx can often reduce the cost further to just a few dollars per month.
Compare prices for Dipyridamole and Ketorolac Tromethamine
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Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.