Drug Comparison

Fluoxetine HCl vs. Labetalol

Compare Fluoxetine HCl and Labetalol: mechanism of action, indications, side effects, cost, and which may be right for you.

Quick Comparison

CategoryFluoxetine HClLabetalol
Drug ClassSSRIs (Selective Serotonin Reuptake Inhibitors)Beta-Blockers
Rx StatusRxRx
Generic AvailableNoNo
Typical Cost$4-$25/month$10–$40/month

Fluoxetine HCl Overview

FLUOXETINE HCL (brand name: Fluoxetine HCL) is a SSRIs. Fluoxetine is indicated for the treatment of: Acute and maintenance treatment of Major Depressive Disorder [see CLINICAL STUDIES (14.1)] . Acute and maintenance treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder (OCD) [see CLINICAL STUDIES (14.2)] . Acute and…

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Labetalol Overview

Labetalol is a medication used to treat high blood pressure (hypertension). It works by relaxing blood vessels and slowing the heart rate, which helps to lower your blood pressure. This can reduce the risk of complications like heart attack and stroke.

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Approved Uses (Indications)

Fluoxetine HCl

Fluoxetine is indicated for the treatment of: Acute and maintenance treatment of Major Depressive Disorder [see CLINICAL STUDIES ] . Acute and maintenance treatment of obsessions and compulsions in patients with Obsessive Compulsive Disorder (OCD) [see CLINICAL STUDIES ] . Acute and maintenance treatment of binge-eating and vomiting behaviors in patients with moderate to severe Bulimia Nervosa [see CLINICAL STUDIES ] . Acute treatment of Panic Disorder, with or without agoraphobia [see CLINICAL STUDIES ] . Fluoxetine and Olanzapine in Combination is indicated for the tr…

Labetalol

INDICATIONS AND USAGE Labetalol hydrochloride tablets, USP are indicated in the management of hypertension. Labetalol hydrochloride tablets, USP may be used alone or in combination with other antihypertensive agents, especially thiazide and loop diuretics.

Side Effects

Fluoxetine HCl

Labetalol

Cost Comparison

Fluoxetine HCl

$4-$25/month

As a widely available generic, Fluoxetine HCl is very affordable. Patients can often find significant savings using discount cards or by checking prices at different pharmacies.

Labetalol

$10–$40/month

Generic labetalol is widely available and typically affordable. Using discount cards or coupons can further reduce the out-of-pocket cost.

Drug Interaction: Minor

Labetalol is primarily metabolized by CYP2D6, but it is not considered a potent substrate like metoprolol or propranolol. Fluoxetine is a potent CYP2D6 inhibitor, but the clinical significance of this interaction with labetalol is generally considered low.

Mechanism: Fluoxetine, a potent CYP2D6 inhibitor, can theoretically decrease the metabolism of labetalol, which is partially metabolized by CYP2D6. This could lead to increased labetalol plasma concentrations.

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Medical Disclaimer

The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.