Anticonvulsants & Gabapentinoids
Anticonvulsants and gabapentinoids are medications that reduce abnormal electrical activity in the brain. They are used to treat epilepsy, neuropathic pain, and certain psychiatric conditions.
Mechanism of Action
These drugs work through multiple mechanisms including blocking voltage-gated calcium channels (gabapentinoids), enhancing GABA activity, and blocking sodium channels to reduce neuronal excitability.
Clinical Uses
Used for epilepsy, neuropathic pain, fibromyalgia, anxiety disorders, bipolar disorder, and restless legs syndrome.
Side Effects & Safety
Common side effects include dizziness, somnolence, ataxia, fatigue, peripheral edema, and cognitive impairment.
Anticonvulsants & Gabapentinoids Medications (1)
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