Biguanides Cost Comparison

Metformin is one of the most affordable medications in the world. Generic metformin immediate-release tablets are available at most major pharmacies for **$4–$15 per month** (500–2,000 mg/day) — often included in $4 generic programs at Walmart, Kroger, and Publix. Extended-release generics typically cost $10–$30 per month. Brand-name Glucophage is rarely prescribed due to cost (up to $300+/month) and identical efficacy of generics. **GoodRx and discount cards** can further reduce costs to under $5/month at many pharmacies. Metformin is covered by virtually all insurance plans, including Medicare Part D, as a Tier 1 (lowest cost) drug. **Combination products** containing metformin (e.g., Janumet = sitagliptin + metformin; Invokamet = canagliflozin + metformin) cost significantly more ($400–$600/month) but may offer convenience. Generic versions of some combinations are now available.

Metformin HCl is available as an inexpensive generic. Patients can often find significant savings using discount cards like GoodRx or by checking pharmacy-specific savings programs.

As a widely available generic, Metformin Hydrochloride is very affordable. Patients can often find the lowest prices using discount cards like GoodRx or through pharmacy savings programs.

As a common generic, Metformin ER is usually affordable. Utilize discount cards like GoodRx or check local pharmacy programs for the best price.