Fluoroquinolones
Fluoroquinolones are a class of broad-spectrum antibiotics used to treat serious bacterial infections including respiratory, urinary tract, and skin infections. They are reserved for moderate-to-severe infections due to their side effect profile.
Mechanism of Action
Fluoroquinolones work by stopping bacteria from growing and multiplying. They do this by blocking two important enzymes inside bacteria called DNA gyrase and topoisomerase IV. These enzymes are crucial for bacteria to copy their genetic material and repair themselves. By blocking these enzymes, fluoroquinolones damage the bacteria's DNA, which ultimately kills the bacteria or stops them from spreading. This targeted action makes them effective against a wide range of bacterial infections.
Clinical Uses
Fluoroquinolones are powerful antibiotics used to treat many types of bacterial infections, especially when other antibiotics might not work or are not tolerated. They are commonly prescribed for serious infections like pneumonia, urinary tract infections, skin infections, and certain types of diarrhea. Specific fluoroquinolones are also used for eye and ear infections. They are often reserved for more severe infections due to potential side effects.
Side Effects & Safety
Common side effects of fluoroquinolones can include nausea, diarrhea, headache, and dizziness. More serious, but less common, side effects can affect tendons (leading to tendonitis or rupture), nerves (causing numbness or tingling), and mental health (like anxiety or confusion). These drugs carry a Black Box Warning from the FDA due to the risk of serious side effects, including tendon rupture, nerve damage, and worsening of myasthenia gravis, which means they should be used with caution and only when necessary.
Conditions Treated
Fluoroquinolones medications are used to treat the following conditions:
Fluoroquinolones Medications (13)
Ciprofloxacin
Brand: Ciprofloxacin
CIPROFLOXACIN (brand name: Ciprofloxacin) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Ciprofloxacin tablets are a fluoroquinolone antibacterial indicated in adults (18 years of age and older) with the following infections caused by designated, susceptible bacteria and in pediatric patients where indicated: • Skin and Skin Structure Infections ( 1.1 ) • Bone…
$10–$50/month/month
Ciprofloxacin hydrochloride
Brand: Ciprofloxacin
CIPROFLOXACIN HYDROCHLORIDE (brand name: Ciprofloxacin) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Ciprofloxacin tablet is a fluoroquinolone antibacterial indicated in adults (18 years of age and older) with the following infections caused by designated, susceptible bacteria and in pediatric patients where indicated: • Skin and Skin Structure Infections ( 1.1 ) • Bone and…
$10–$50/month/month
Ciprofloxacin otic solution, 0.2%
Brand: Ciprofloxacin Otic Solution, 0.2%
CIPROFLOXACIN OTIC SOLUTION, 0.2% (brand name: Ciprofloxacin Otic Solution, 0.2%) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Ciprofloxacin otic solution, 0.2% is a quinolone antimicrobial indicated for the treatment of acute otitis externa due to susceptible isolates of Pseudomonas aeruginosa or Staphylococcus aureus . Ciprofloxacin otic solution, 0.2% is a quinolone antimicrobial indicated for…
$150–$350/month/month
Levofloxacin
Brand: levofloxacin
LEVOFLOXACIN (brand name: levofloxacin) is a Fluoroquinolones. used to treat serious bacterial infections including respiratory, urinary, and skin infections.
$15–$50/month/month
Levofloxacin in 5% dextrose
Brand: Levofloxacin
LEVOFLOXACIN IN 5% DEXTROSE (brand name: Levofloxacin) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Levofloxacin injection is indicated for the treatment of adults (≥18 years of age) with mild, moderate, and severe infections caused by susceptible isolates of the designated microorganisms in the conditions listed in this section. Levofloxacin injection is indicated when…
$200–$800/month/month
Llevofloxacin
Brand: Levofloxacin
LLEVOFLOXACIN (brand name: Levofloxacin) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Levofloxacin is a fluoroquinolone antibacterial indicated in adults (18 years of age and older) with infections caused by designated, susceptible bacteria and in pediatric patients where indicated ( 1 , 12.4 ). Pneumonia: Nosocomial ( 1.1 ) and Community Acquired ( 1.2 , 1.3…
$20–$70/month/month
Moxifloxacin
Brand: Moxifloxacin
MOXIFLOXACIN (brand name: Moxifloxacin) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Moxifloxacin ophthalmic solution, 0.5% is a topical fluoroquinolone anti- infective indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Corynebacterium species*, Micrococcus luteus*, Staphylococcus aureus,…
$50–$200/month/month
Moxifloxacin 0.5%, bromfenac 0.09%, prednisolone acetate 1%
Brand: Strenza Plus
MOXIFLOXACIN 0.5%, BROMFENAC 0.09%, PREDNISOLONE ACETATE 1% (brand name: STRENZA PLUS) is a Fluoroquinolones. used to treat serious bacterial infections including respiratory, urinary, and skin infections.
$300-$700/month/month
Moxifloxacin hydrochloride
Brand: Moxifloxacin Hydrochloride
MOXIFLOXACIN HYDROCHLORIDE (brand name: Moxifloxacin Hydrochloride) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Moxifloxacin tablets are a fluoroquinolone antibacterial indicated for treating infections in adults 18 years of age and older caused by designated susceptible bacteria, in the conditions listed below: Community Acquired Pneumonia ( 1.1 ) Skin and Skin Structure Infections:…
$200–$500/prescription/month
Moxifloxacin hydrochloride tablets, 400 mg
Brand: Moxifloxacin Hydrochloride Tablets, 400 mg
MOXIFLOXACIN HYDROCHLORIDE TABLETS, 400 MG (brand name: Moxifloxacin Hydrochloride Tablets, 400 mg) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Moxifloxacin tablets are a fluoroquinolone antibacterial indicated for treating infections in adults 18 years of age and older caused by designated susceptible bacteria, in the conditions listed below: Community Acquired Pneumonia ( 1.1 ) Skin and Skin Structure Infections:…
$200–$500/month/month
Moxifloxacin ophthalmic solution
Brand: Moxifloxacin ophthalmic solution
MOXIFLOXACIN OPHTHALMIC SOLUTION (brand name: Moxifloxacin ophthalmic solution) is a Fluoroquinolones. 1 INDICATIONS AND USAGE Moxifloxacin ophthalmic solution is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: Corynebacterium species* Micrococcus luteus* Staphylococcus aureus Staphylococcus epidermidis Staphylococcus haemolyticus…
$150–$350/month/month
Ofloxacin
Brand: Ofloxacin
OFLOXACIN (brand name: Ofloxacin) is a Fluoroquinolones. INDICATIONS AND USAGE Ofloxacin otic solution 0.3% is indicated for the treatment of infections caused by susceptible isolates of the designated microorganisms in the specific conditions listed below: Otitis Externa in adults and pediatric patients, 6 months and older, due to Escherichia coli,…
$10–$50/month/month
Ofloxacin otic
Brand: Ofloxacin
OFLOXACIN OTIC (brand name: Ofloxacin) is a Fluoroquinolones. INDICATIONS AND USAGE Ofloxacin Otic Solution 0.3% is indicated for the treatment of infections caused by susceptible isolates of the designated microorganisms in the specific conditions listed below: Otitis Externa in adults and pediatric patients, 6 months and older, due to Escherichia coli,…
$100–$250/month/month
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