NSAIDs Cost Comparison
Compare prices for all 26 NSAIDs medications. Find the cheapest generic options, coupon availability, and patient assistance programs. Includes typical monthly costs with and without insurance.
Price Comparison Table(sorted cheapest first)
| Drug (Generic) | Brand Names | Typical Monthly Cost | Generic | Coupon | Manufacturers | |
|---|---|---|---|---|---|---|
Ibuprofen Rx | good neighbor pharmacy ibuprofen | $4-$15/month Budget-Friendly | 6 | Full details | ||
Meloxicam Rx | meloxicam | $4–$20/month Budget-Friendly | 6 | Full details | ||
Naproxen Rx | Naproxen | $4–$25/month Budget-Friendly | 6 | Full details | ||
Acetaminophen, aspirin, caffeine Rx | Headache Relief | $5–$20/month Budget-Friendly | — | Full details | ||
Acetaminophen, aspirin, caffeine tablet Rx | Extra Strength Headache, Caseys 4good | $5–$20/month Budget-Friendly | — | Full details | ||
Aspirin Rx | Aspirin Regular Strength | $5–$20/month Budget-Friendly | — | Full details | ||
Aspirin 81 mg Rx | Aspirin Enteric Coated | $5–$20/month Budget-Friendly | — | Full details | ||
Alka-seltzer original flavor Rx | Alka-Seltzer Original Flavor | $10–$30/month Budget-Friendly | — | Full details | ||
Diclofenac sodium Rx | Diclofenac Sodium | $10-$30/month Budget-Friendly | 6 | Full details | ||
Diphenhydramine citrate, ibuprofen Rx | good sense ibuprofen pm | $10–$30/month Budget-Friendly | — | Full details | ||
Ibuprofen tablet, film-coated Rx | Ibuprofen, Caseys 4good | $10–$30/month Budget-Friendly | — | Full details | ||
Ibuprofen, phenylephrine hcl Rx | Equaline congestion relief | $10–$30/month Budget-Friendly | — | Full details | ||
Ketorolac tromethamine Rx | Ketorolac Tromethamine | $10–$50/month Budget-Friendly | 6 | Full details | ||
Piroxicam Rx | Piroxicam | $10–$30/month Budget-Friendly | 5 | Full details | ||
Acetaminophen, ibuprofen Rx | Dual Action Pain Relief | $15–$40/month Budget-Friendly | — | Full details | ||
Etodolac Rx | Etodolac | $15-$60/month Budget-Friendly | 6 | Full details | ||
Ibuprofen, acetaminophen tablet, film coated Rx | Advil Dual Action with Acetaminophen, Travel BASIX, Advil Dual Action with Acetaminophen | $15–$40/month Budget-Friendly | — | Full details | ||
Nabumetone Rx | Nabumetone | $15–$50/month Budget-Friendly | 5 | Full details | ||
Naproxen sodium 220mg Rx | Naproxen Sodium 220mg | $15–$40/month Budget-Friendly | — | Full details | ||
Sulindac Rx | SULINDAC | $15-$40/month Budget-Friendly | 6 | Full details | ||
Diclofenac sodium topical gel, 1% Rx | DICLOFENAC SODIUM | $20–$60/month Moderate Cost | 6 | Full details | ||
Ibuprofen tablets Rx | Ibuprofen, Caseys 4good | $20–$50/month Moderate Cost | — | Full details | ||
Naproxen sodium Rx | All Day Back and Muscle Pain Relief | $20–$60/month Moderate Cost | — | Full details | ||
Indomethacin Rx | Indomethacin | $30–$80/month Moderate Cost | — | Full details | ||
Celecoxib Rx | celecoxib | $150–$400/month Higher Cost | — | Full details | ||
Diclofenac sodium, capsaicin Rx | Lextol | $200–$500/month Higher Cost | — | Full details |
Ibuprofen
good neighbor pharmacy ibuprofen
Meloxicam
meloxicam
Naproxen
Naproxen
Acetaminophen, aspirin, caffeine
Headache Relief
Acetaminophen, aspirin, caffeine tablet
Extra Strength Headache, Caseys 4good
Aspirin
Aspirin Regular Strength
Aspirin 81 mg
Aspirin Enteric Coated
Alka-seltzer original flavor
Alka-Seltzer Original Flavor
Diclofenac sodium
Diclofenac Sodium
Diphenhydramine citrate, ibuprofen
good sense ibuprofen pm
Ibuprofen tablet, film-coated
Ibuprofen, Caseys 4good
Ibuprofen, phenylephrine hcl
Equaline congestion relief
Ketorolac tromethamine
Ketorolac Tromethamine
Piroxicam
Piroxicam
Acetaminophen, ibuprofen
Dual Action Pain Relief
Etodolac
Etodolac
Ibuprofen, acetaminophen tablet, film coated
Advil Dual Action with Acetaminophen, Travel BASIX, Advil Dual Action with Acetaminophen
Nabumetone
Nabumetone
Naproxen sodium 220mg
Naproxen Sodium 220mg
Sulindac
SULINDAC
Diclofenac sodium topical gel, 1%
DICLOFENAC SODIUM
Ibuprofen tablets
Ibuprofen, Caseys 4good
Naproxen sodium
All Day Back and Muscle Pain Relief
Indomethacin
Indomethacin
Celecoxib
celecoxib
Diclofenac sodium, capsaicin
Lextol
Cost Notes by Drug
Ibuprofen is widely available as an inexpensive generic, even without insurance. Discount cards can further reduce the cost at many pharmacies.
Meloxicam is available as an inexpensive generic. Patients can significantly reduce costs using discount cards or by checking prices at different pharmacies.
Naproxen is widely available as an affordable generic. Using discount cards like GoodRx can further reduce the cost, often bringing it to under $10 per month.
As an over-the-counter combination, this medication is generally inexpensive. Look for store brands or use coupons from retailers to save money.
This combination drug is available over-the-counter and is very inexpensive. Look for store brands or use discount coupons to find the lowest price.
Aspirin is available over-the-counter at a very low cost, often less than $5 for a large supply. Discount cards can sometimes offer minor savings on the prescription version, but it's generally more cost-effective to buy OTC.
Despite being a brand, Aspirin 81 mg is very inexpensive. Look for store brand or generic aspirin for even lower prices, and discount cards can often reduce the cost further.
Alka-Seltzer Original Flavor is an over-the-counter product, but if prescribed, discount cards can often help reduce the cost. Compare prices at different pharmacies as they can vary.
Diclofenac sodium is widely available as a low-cost generic. Patients can often find significant savings by using discount cards or pharmacy loyalty programs.
Since this is a combination of two common over-the-counter medications, purchasing generic diphenhydramine and ibuprofen separately may offer additional savings. Discount cards can also help reduce the cost.
While Ibuprofen is available over-the-counter for lower doses, the prescription strength may be covered by insurance or significantly reduced with discount cards like GoodRx.
As this is a combination of two common, inexpensive ingredients, even without insurance, the cost is typically low. Look for store brands or generic versions of similar over-the-counter products for the best price.
As a widely available generic, Ketorolac Tromethamine is typically inexpensive. Using discount cards like GoodRx can often reduce the cost further to just a few dollars per month.
Piroxicam is available as an affordable generic. Patients can often find significant savings by using discount cards or coupons from services like GoodRx.
Although this specific combination is brand-only, acetaminophen and ibuprofen are widely available as inexpensive generics. Discount cards or coupons can often help reduce the cost of the brand-name product.
Since Etodolac is available as a generic, using discount cards like GoodRx can significantly reduce the cash price. Always compare prices at different pharmacies.
As a brand-name, non-generic drug, prices can vary. Look for manufacturer coupons or use discount cards like GoodRx to help reduce the cost.
Nabumetone is available as a generic, which significantly lowers its cost. Using discount cards like GoodRx can further reduce the price to as little as $15-20 per month.
While the 220mg strength might be marketed as a brand, naproxen sodium is widely available as a low-cost generic. Using discount cards or checking prices at different pharmacies can significantly reduce your out-of-pocket cost.
As a generic medication, Sulindac is relatively inexpensive. Patients can often find significant savings by using discount cards or checking prices at different pharmacies.
Diclofenac Sodium Topical Gel is available as a generic, which is significantly cheaper than brand-name options. Using discount coupons from services like GoodRx can further reduce the out-of-pocket cost.
While Ibuprofen is widely available as a low-cost generic, this specific brand-name version may be more expensive. Patients can often find significant savings by using discount cards or asking their pharmacist about generic alternatives.
While a generic prescription is not available, discount cards can often significantly reduce the cost of brand-name Naproxen Sodium. Check for manufacturer coupons as well.
While Indomethacin is available generically, its brand name is also Indomethacin. Using discount cards like GoodRx can often help reduce the cost significantly.
Since Celecoxib is available as a generic, comparing prices at different pharmacies and using discount cards like GoodRx can significantly reduce your out-of-pocket cost. Some manufacturers also offer patient assistance programs for those who qualify.
Since Lextol is a brand-only medication, look for manufacturer coupons or patient assistance programs to help reduce the cost. Discount cards like GoodRx may also offer some savings.
How to Save on NSAIDs Medications
Choose a Generic
0 of 26 NSAIDs drugs have generic versions available, which can cost 80–90% less than brand-name versions.
Use a Discount Card
GoodRx, RxSaver, and Blink Health can reduce out-of-pocket costs at most pharmacies, even if you have insurance.
Ask About 90-Day Supplies
Mail-order pharmacies often charge less per dose for 90-day fills compared to monthly fills at retail pharmacies.
Patient Assistance Programs
If you're uninsured or underinsured, NeedyMeds and RxAssist can connect you with manufacturer PAPs that may provide medications at no cost.
More NSAIDs Resources
Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.