RxGuide
Drug Class1 Medications1 Generics Available

Thyroid Hormones

Thyroid hormone replacements are synthetic versions of the hormones produced by the thyroid gland. They are used to treat hypothyroidism and thyroid cancer, and to suppress TSH in certain thyroid conditions.

Mechanism of Action

Levothyroxine (T4) is converted to the active form triiodothyronine (T3) in peripheral tissues. T3 binds to nuclear thyroid hormone receptors and regulates gene transcription, controlling metabolism, growth, and development.

Clinical Uses

Used for hypothyroidism, thyroid cancer (TSH suppression), myxedema coma, goiter, and Hashimoto's thyroiditis.

Side Effects & Safety

Side effects from excess dosing include palpitations, tachycardia, tremor, weight loss, insomnia, heat intolerance, and excessive sweating.

Thyroid Hormones Medications (1)

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Levothyroxine sodium

Brand: Synthroid, Levoxyl, Unithroid +1 more

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Levothyroxine (Synthroid) is a synthetic thyroid hormone used to treat hypothyroidism (underactive thyroid) and to suppress TSH in thyroid cancer patients. It is the third most prescribed medication in the United States. Generic levothyroxine is widely available and typically costs $10–$30 per month.

$10–$30/month/month

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Medical Disclaimer

The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.