Empagliflozin, metformin hydrochloride Cost & Price Guide

Also sold as: Synjardy XR

Since there is no generic available, look for manufacturer coupons or patient assistance programs to significantly reduce the cost of Synjardy XR.

Typical Cost
$500–$800/month

Per month, without insurance

Generic
Not Available

Only brand-name versions currently available

Coupons
Available

Discount coupons may reduce out-of-pocket costs

Cost Overview

Since there is no generic available, look for manufacturer coupons or patient assistance programs to significantly reduce the cost of Synjardy XR.

Generic vs. Brand-Name Price

VersionTypical Monthly CostNotes
Synjardy XR(brand)$500–$800/monthCheck manufacturer patient assistance programs

Ways to Save on Empagliflozin, metformin hydrochloride

Prescription Discount Cards

Free discount programs like GoodRx, RxSaver, and NeedyMeds can reduce the cost of empagliflozin, metformin hydrochloride at most pharmacies. Compare prices before filling.

90-Day Supply

Ordering a 90-day supply through a mail-order pharmacy often costs less per dose than monthly fills. Check with your insurance plan or pharmacy benefit manager.

Patient Assistance Programs

If you're uninsured or underinsured, the manufacturer may offer a patient assistance program (PAP) that provides empagliflozin, metformin hydrochloride at low or no cost. Visit NeedyMeds.org or the manufacturer's website.

Insurance Coverage

Most insurance plans, including Medicare Part D and Medicaid, cover empagliflozin, metformin hydrochloride . Coverage and copay amounts vary by plan tier and formulary. Contact your insurance provider or check your plan's drug formulary to confirm coverage.

Medicare Part D
Usually covered; tier varies by plan
Medicaid
Generally covered; check your state plan
Commercial Insurance
Typically covered; copay varies

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Frequently Asked Questions About Empagliflozin, metformin hydrochloride Cost

What is EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE used for?

1 INDICATIONS AND USAGE SYNJARDY SYNJARDY is a combination of empagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor and metformin hydrochloride (HCl) immediate-release, a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus. SYNJARDY XR SYNJARDY XR is a combination of empagliflozin, a SGLT2 inhibitor and metformin HCl extended-release, a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus .…

What is the recommended dosage for EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE?

2 DOSAGE AND ADMINISTRATION Assess renal function before initiating and as clinically indicated. Assess volume status and correct volume depletion before initiating. ( 2.1 ) Individualize the starting dosage based on the patient's current regimen and renal function. ( 2.2 , 2.3 , 2.4 ) The maximum recommended dosage is 25 mg/day of empagliflozin and 2,000 mg/day of metformin HCl. ( 2.2 , 2.3 ) Initiation of SYNJARDY or SYNJARDY XR is not recommended in patients with an eGFR less than 45 mL/min/1.73 m 2 , due to the metformin HCl component. ( 2.4 ) SYNJARDY: take orally twice daily with meals,…

How does EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE work?

12.1 Mechanism of Action SYNJARDY or SYNJARDY XR SYNJARDY and SYNJARDY XR contain: empagliflozin, a SGLT2 inhibitor, and metformin HCl, a biguanide. Empagliflozin Empagliflozin is an inhibitor of SGLT2, the predominant transporter responsible for reabsorption of glucose from the glomerular filtrate back into the circulation. By inhibiting SGLT2, empagliflozin reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion. Empagliflozin also reduces sodium reabsorption and increases the delivery of sodium to the distal…

Who should not take EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE?

4 CONTRAINDICATIONS SYNJARDY and SYNJARDY XR are contraindicated in patients with: severe renal impairment (eGFR less than 30 mL/min/1.73 m 2 ) [see Warnings and Precautions (5.1) and Use in Specific Populations (8.6) ]. acute or chronic metabolic acidosis, including diabetic ketoacidosis [see Warnings and Precautions (5.1) ]. hypersensitivity to empagliflozin, metformin HCl or any of the excipients in SYNJARDY or SYNJARDY XR, reactions such as angioedema have occurred [see Warnings and Precautions (5.7) ] . Severe renal impairment (eGFR below 30 mL/min/1.73 m 2 ) ( 4 ) Metabolic acidosis,…

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