Losartan potassium Cost & Price Guide
Also sold as: Cozaar, Hyzaar (with hydrochlorothiazide)
Generic losartan potassium is available at most pharmacies for $4–$15/month, and is included on most $4 generic drug programs at major pharmacy chains (Walmart, Kroger, Costco). Brand-name Cozaar is significantly more expensive (~$200–$300/month) but is rarely prescribed. Hyzaar (losartan/hydrochlorothiazide combination) is also available generically at similar low cost. GoodRx and RxGo coupons can further reduce the price at most pharmacies.
Per month, without insurance
Only brand-name versions currently available
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Cost Overview
Generic losartan potassium is available at most pharmacies for $4–$15/month, and is included on most $4 generic drug programs at major pharmacy chains (Walmart, Kroger, Costco). Brand-name Cozaar is significantly more expensive (~$200–$300/month) but is rarely prescribed. Hyzaar (losartan/hydrochlorothiazide combination) is also available generically at similar low cost. GoodRx and RxGo coupons can further reduce the price at most pharmacies.
Generic vs. Brand-Name Price
| Version | Typical Monthly Cost | Notes |
|---|---|---|
| Cozaar(brand) | $4–$15/month | Check manufacturer patient assistance programs |
| Hyzaar (with hydrochlorothiazide)(brand) | $4–$15/month | Check manufacturer patient assistance programs |
Generic Manufacturers
The following companies manufacture FDA-approved generic versions of Losartan potassium. Prices may vary between manufacturers and pharmacies.
Ways to Save on Losartan potassium
Prescription Discount Cards
Free discount programs like GoodRx, RxSaver, and NeedyMeds can reduce the cost of losartan potassium at most pharmacies. Compare prices before filling.
90-Day Supply
Ordering a 90-day supply through a mail-order pharmacy often costs less per dose than monthly fills. Check with your insurance plan or pharmacy benefit manager.
Patient Assistance Programs
If you're uninsured or underinsured, the manufacturer may offer a patient assistance program (PAP) that provides losartan potassium at low or no cost. Visit NeedyMeds.org or the manufacturer's website.
Insurance Coverage
Most insurance plans, including Medicare Part D and Medicaid, cover losartan potassium . Coverage and copay amounts vary by plan tier and formulary. Contact your insurance provider or check your plan's drug formulary to confirm coverage.
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Patient Assistance Programs (PAP)
If you're uninsured, underinsured, or cannot afford losartan potassium, these programs may provide it at low or no cost.
Frequently Asked Questions About Losartan potassium Cost
Why doesn't losartan cause a dry cough like lisinopril?
ACE inhibitors like lisinopril block the ACE enzyme, which also breaks down bradykinin. When bradykinin accumulates in the lungs, it triggers a dry cough in 10–20% of patients. Losartan works differently — it blocks the AT1 receptor where angiotensin II acts, but does not affect ACE or bradykinin levels. This is why losartan is the standard alternative for patients who cannot tolerate ACE inhibitor-induced cough.
What is the uricosuric effect of losartan?
Losartan is the only ARB that lowers serum uric acid levels. It inhibits the URAT1 urate transporter in the kidney, increasing uric acid excretion in the urine. This typically reduces serum uric acid by 15–20%. This effect makes losartan a preferred choice for patients who have both hypertension and gout or hyperuricemia. No other ARB (valsartan, olmesartan, irbesartan, telmisartan) shares this property.
What did the LIFE trial show about losartan?
The LIFE trial (2002) compared losartan to atenolol in 9,193 patients with hypertension and left ventricular hypertrophy over 4.8 years. Losartan reduced the composite of cardiovascular death, MI, and stroke by 13% compared to atenolol, despite similar blood pressure reduction. The stroke reduction was 25% greater with losartan. This trial established losartan as the preferred agent for hypertension with LVH.
Can losartan be used in patients with diabetes and kidney disease?
Yes — losartan is specifically FDA-approved for diabetic nephropathy. The RENAAL trial showed that losartan reduced the risk of doubling serum creatinine by 25% and end-stage renal disease by 28% in patients with type 2 diabetes and nephropathy. It also significantly reduced proteinuria. Losartan is recommended by JNC 8, ADA, and KDIGO guidelines as first-line therapy for hypertension in patients with type 2 diabetes and CKD.
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The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.