Methadone Cost & Price Guide

Also sold as: Methadone Hydrochloride

Generic methadone is very affordable, especially with discount cards like GoodRx. Many pharmacies offer low-cost programs for this medication.

Typical Cost
$15–$60/month

Per month, without insurance

Generic
Not Available

Only brand-name versions currently available

Coupons
Available

Discount coupons may reduce out-of-pocket costs

Cost Overview

Generic methadone is very affordable, especially with discount cards like GoodRx. Many pharmacies offer low-cost programs for this medication.

Generic vs. Brand-Name Price

VersionTypical Monthly CostNotes
Methadone Hydrochloride(brand)$15–$60/monthCheck manufacturer patient assistance programs

Generic Manufacturers

The following companies manufacture FDA-approved generic versions of Methadone. Prices may vary between manufacturers and pharmacies.

Mallinckrodt
Roxane Laboratories
Hikma
Amneal Pharmaceuticals
West-Ward Pharmaceuticals

Ways to Save on Methadone

Prescription Discount Cards

Free discount programs like GoodRx, RxSaver, and NeedyMeds can reduce the cost of methadone at most pharmacies. Compare prices before filling.

90-Day Supply

Ordering a 90-day supply through a mail-order pharmacy often costs less per dose than monthly fills. Check with your insurance plan or pharmacy benefit manager.

Patient Assistance Programs

If you're uninsured or underinsured, the manufacturer may offer a patient assistance program (PAP) that provides methadone at low or no cost. Visit NeedyMeds.org or the manufacturer's website.

Insurance Coverage

Most insurance plans, including Medicare Part D and Medicaid, cover methadone . Coverage and copay amounts vary by plan tier and formulary. Contact your insurance provider or check your plan's drug formulary to confirm coverage.

Medicare Part D
Usually covered; tier varies by plan
Medicaid
Generally covered; check your state plan
Commercial Insurance
Typically covered; copay varies

Find the Best Price

Frequently Asked Questions About Methadone Cost

What is METHADONE used for?

1 INDICATIONS AND USAGE Methadone hydrochloride tablets is indicated for the: Management of severe and persistent pain that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids. Limitations of Use Because of the risks of addiction, abuse, misuse, overdose, and death, which can occur at any dosage or duration and persist over the course of therapy [see WARNINGS AND PRECAUTIONS ( 5.1 )], reserve opioid analgesics, including methadone hydrochloride tablets, for use in patients for whom alternative analgesic treatment…

What is the recommended dosage for METHADONE?

2 DOSAGE AND ADMINISTRATION Consider recommending or prescribing an opioid overdose reversal agent (e.g., naloxone, nalmefene) based on the patient’s risk factors for overdose ( 2.3 , 5.1 , 5.2 , 5.3 ). Methadone hydrochloride tablets should be prescribed only by healthcare professionals who are knowledgeable about the use of extended-release/long-acting opioids and how to mitigate the associated risks. ( 2.1 ) Use the lowest effective dosage for the shortest duration of time consistent with individual patient treatment goals. Reserve titration to higher doses of methadone hydrochloride…

How does METHADONE work?

12.1 Mechanism of Action Methadone hydrochloride is a mu-agonist; a synthetic opioid with multiple actions qualitatively similar to those of morphine, the most prominent of which involves the central nervous system and organs composed of smooth muscle. The principal therapeutic uses for methadone are for analgesia and for detoxification or maintenance in opioid addiction. The methadone withdrawal syndrome, although qualitatively similar to that of morphine, differs in that the onset is slower, the course is more prolonged, and the symptoms are less severe. Some data also indicate that…

Who should not take METHADONE?

4 CONTRAINDICATIONS Methadone hydrochloride tablets are contraindicated in patients with: Significant respiratory depression [see WARNINGS AND PRECAUTIONS ( 5.2 ) ]. Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment [see WARNINGS AND PRECAUTIONS ( 5.10 ) ]. Known or suspected gastrointestinal obstruction, including paralytic ileus [see WARNINGS AND PRECAUTIONS ( 5.14 ) ]. Hypersensitivity (e.g., anaphylaxis) to methadone [see ADVERSE REACTIONS ( 6 ) ]. Significant respiratory depression ( 4 ) Acute or severe bronchial asthma in an…

More Methadone Information

Medical Disclaimer

The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.