Opioid Analgesics Cost Comparison
Compare prices for all 25 Opioid Analgesics medications. Find the cheapest generic options, coupon availability, and patient assistance programs. Includes typical monthly costs with and without insurance.
Price Comparison Table(sorted cheapest first)
| Drug (Generic) | Brand Names | Typical Monthly Cost | Generic | Coupon | Manufacturers | |
|---|---|---|---|---|---|---|
Codeine sulfate Rx | Codeine sulfate | $10–$50/month Budget-Friendly | — | Full details | ||
Methadone Rx | Methadone Hydrochloride | $15–$60/month Budget-Friendly | 5 | Full details | ||
Tramadol hydrochloride Rx | TRAMADOL HYDROCHLORIDE | $15–$50/month Budget-Friendly | — | Full details | ||
Morphine sulfate Rx | Morphine Sulfate | $20–$150/month Moderate Cost | — | Full details | ||
Methadone hydrochloride Rx | Methadone Hydrochloride | $30–$150/month Moderate Cost | — | Full details | ||
Oxycodone hydrochloride oral solution Rx | Oxycodone Hydrochloride Oral Solution | $30–$100/month Moderate Cost | — | Full details | ||
Buprenorphine Rx | BUPRENORPHINE | $50–$300/month Moderate Cost | — | Full details | ||
Morphine tincture Rx | Opium Tincture Deodorized | $50–$150/month Moderate Cost | — | Full details | ||
Oxycodone hydrochloride Rx | Oxycodone Hydrochloride | $50–$300/month Moderate Cost | — | Full details | ||
Buprenorphine sublingual Rx | Buprenorphine Sublingual | $100–$300/month Higher Cost | — | Full details | ||
Nalbuphine hydrochloride Rx | Nalbuphine Hydrochloride | $100–$400/month Higher Cost | — | Full details | ||
Fentanyl Rx | FENTANYL | $150–$600/month Higher Cost | — | Full details | ||
Fentanyl transdermal Rx | FENTANYL TRANSDERMAL | $150–$400/month Higher Cost | — | Full details | ||
Hydrocodone bitartrate C-II | Zohydro ER | $150-$400/month Higher Cost | 1 | Full details | ||
Buprenorphine hydrochloride Rx | buprenorphine hydrochloride | $200–$600/month Higher Cost | — | Full details | ||
Buprenorphine sublingual c-iii Rx | Buprenorphine Sublingual C-III | $200–$600/month Higher Cost | — | Full details | ||
Hydromorphone hydrochloride Rx | Hydromorphone Hydrochloride | $200–$500/month Higher Cost | — | — | Full details | |
Morphine Rx | Opium Tincture Deodorized | $200–$600/month Higher Cost | — | Full details | ||
Oxycodone Rx | Oxycodone Hydrochloride | $200–$600/month Higher Cost | — | Full details | ||
Oxymorphone hydrochloride Rx | Oxymorphone Hydrochloride | $200–$800/month Higher Cost | — | Full details | ||
Sufentanil Rx | Dsuvia | $200–$500 per dose Higher Cost | — | — | Full details | |
Tramadol hcl er Rx | Tramadol HCL ER | $200–$600/month Higher Cost | — | Full details | ||
Tapentadol hydrochloride Rx | Tapentadol Hydrochloride | $300–$800/month Higher Cost | — | Full details | ||
Fentanyl citrate Rx | Fentanyl Citrate | $500–$2,000+/month Higher Cost | — | Full details | ||
Nalbuphine hci Rx | NALBUPHINE HCI | $500–$1,500/month Higher Cost | — | Full details |
Codeine sulfate
Codeine sulfate
Methadone
Methadone Hydrochloride
Tramadol hydrochloride
TRAMADOL HYDROCHLORIDE
Morphine sulfate
Morphine Sulfate
Methadone hydrochloride
Methadone Hydrochloride
Oxycodone hydrochloride oral solution
Oxycodone Hydrochloride Oral Solution
Buprenorphine
BUPRENORPHINE
Morphine tincture
Opium Tincture Deodorized
Oxycodone hydrochloride
Oxycodone Hydrochloride
Buprenorphine sublingual
Buprenorphine Sublingual
Nalbuphine hydrochloride
Nalbuphine Hydrochloride
Fentanyl
FENTANYL
Fentanyl transdermal
FENTANYL TRANSDERMAL
Hydrocodone bitartrate
Zohydro ER
Buprenorphine hydrochloride
buprenorphine hydrochloride
Buprenorphine sublingual c-iii
Buprenorphine Sublingual C-III
Hydromorphone hydrochloride
Hydromorphone Hydrochloride
Morphine
Opium Tincture Deodorized
Oxycodone
Oxycodone Hydrochloride
Oxymorphone hydrochloride
Oxymorphone Hydrochloride
Sufentanil
Dsuvia
Tramadol hcl er
Tramadol HCL ER
Tapentadol hydrochloride
Tapentadol Hydrochloride
Fentanyl citrate
Fentanyl Citrate
Nalbuphine hci
NALBUPHINE HCI
Cost Notes by Drug
As a generic medication, Codeine Sulfate is relatively inexpensive. Using a discount card or coupon can often reduce the cash price further.
Generic methadone is very affordable, especially with discount cards like GoodRx. Many pharmacies offer low-cost programs for this medication.
Tramadol Hydrochloride is available as a generic, making it generally affordable. Using discount cards like GoodRx can further reduce the cost, often bringing it down to under $20 per month.
Despite being a brand-only drug, Morphine Sulfate is often available at a lower cost than many other brand medications. Always check with discount cards and compare pharmacy prices to find the best deal.
Even though a generic is not available, discount cards can often significantly reduce the out-of-pocket cost for methadone. Always compare prices at different pharmacies.
While there are no generic manufacturers for this specific oral solution, discount cards like GoodRx can often help reduce the out-of-pocket cost significantly. Always compare prices at different pharmacies.
While Buprenorphine is available as a generic, prices can vary significantly depending on the specific formulation and dosage. Using discount cards like GoodRx can often help reduce the out-of-pocket cost.
As this is a brand-only medication, discount cards or manufacturer coupons may help reduce the out-of-pocket cost. Patients should inquire about patient assistance programs if costs remain a barrier.
While a generic is not available, discount cards like GoodRx can often help reduce the cost. Patients should also inquire about patient assistance programs offered by manufacturers or non-profit organizations.
As this is a brand-only medication, look for manufacturer coupons or patient assistance programs. Discount cards like GoodRx can also help reduce the out-of-pocket cost.
Since Nalbuphine Hydrochloride is often administered in a clinical setting, out-of-pocket costs may be covered by your medical insurance. For outpatient prescriptions, discount cards or patient assistance programs may offer significant savings.
As a brand-only medication, fentanyl can be expensive. Patients should check for manufacturer coupons or patient assistance programs, and compare prices at different pharmacies using discount cards.
Although there is no generic, manufacturer coupons or patient assistance programs may significantly reduce the cost of Fentanyl Transdermal. Always compare prices at different pharmacies and consider discount cards.
Generic versions of extended-release hydrocodone are not widely available under this specific formulation (Zohydro ER was a brand name for a pure hydrocodone ER product). Costs can vary significantly based on insurance coverage and pharmacy. Manufacturer coupons or patient assistance programs may be available.
Since buprenorphine hydrochloride is currently brand-only, consider manufacturer patient assistance programs. Discount cards may offer some savings, but the cost without insurance remains significant.
As there is no generic available, look for manufacturer coupons or patient assistance programs to significantly reduce the cost. Discount cards like GoodRx may also offer some savings.
As a brand-only medication, costs without insurance can be high. Discuss patient assistance programs with your doctor or pharmacist for potential savings.
As there is no generic available, patients should look for manufacturer patient assistance programs or discount cards to help reduce the cost of Opium Tincture Deodorized.
As a brand-name medication, costs can be high without insurance. Manufacturer coupons or patient assistance programs may offer significant savings.
Since a generic is not available, patients may find discounts using manufacturer coupons or patient assistance programs. Comparing prices at different pharmacies with discount cards can also help reduce costs.
Dsuvia is a brand-only medication typically administered in a supervised medical setting, making direct patient purchase and coupon use uncommon. Cost is usually covered by insurance or the facility.
As a brand-only medication, costs can be high without insurance. Look for manufacturer coupons or patient assistance programs, and compare prices at different pharmacies using discount cards.
Since Tapentadol Hydrochloride is only available as a brand-name drug, look for manufacturer coupons or patient assistance programs to significantly reduce costs. Discount cards like GoodRx can also offer some savings.
Since Fentanyl Citrate is a brand-name drug, look for manufacturer patient assistance programs or coupons to significantly reduce costs. Discount cards like GoodRx may also offer some savings.
As Nalbuphine HCl is a brand-only medication, costs can be high without insurance. Look for manufacturer patient assistance programs or discount cards like GoodRx to help reduce the price.
How to Save on Opioid Analgesics Medications
Choose a Generic
1 of 25 Opioid Analgesics drugs have generic versions available, which can cost 80–90% less than brand-name versions.
Use a Discount Card
GoodRx, RxSaver, and Blink Health can reduce out-of-pocket costs at most pharmacies, even if you have insurance.
Ask About 90-Day Supplies
Mail-order pharmacies often charge less per dose for 90-day fills compared to monthly fills at retail pharmacies.
Patient Assistance Programs
If you're uninsured or underinsured, NeedyMeds and RxAssist can connect you with manufacturer PAPs that may provide medications at no cost.
More Opioid Analgesics Resources
Medical Disclaimer
The information on RxGuide is intended for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician, pharmacist, or other qualified health provider with any questions you may have regarding a medical condition or medication. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.